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lumacaftor/ivacaftor will decrease the level or result of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of abemaciclib with powerful CYP3A4 inducers lowers plasma focus of abemaciclib and its metabolites.So you know particularly how the solution must search, go through th